R-410ASafety Data SheetR-410A1.CHEMICAL PRODUCT AND COMPANY IDENTIFICATIONPRODUCT NAME:OTHER NAME:USE:R-410ADifluoromethane, PentafluoroethaneRefrigerant GasDISTRIBUTOR:National Refrigerants, Inc.661 Kenyon AvenueBridgeton, New Jersey 08302FOR MORE INFORMATION CALL:(Monday-Friday, 8:00am-5:00pm)1-800-262-00122.IN CASE OF EMERGENCY CALL:CHEMTREC: 1-800-424-9300HAZARDS IDENTIFICATIONCLASSIFICATION:SIGNAL WORD:HAZARD STATEMENT:SYMBOL:PRECAUTIONARY STATEMENT:Gases under pressure, Liquefied GasWARNINGContains gas under pressure, may explode if heatedGas CylinderSTORAGE: Protect from sunlight, store in a well ventilated placeEMERGENCY OVERVIEW: Colorless, volatile liquid with ethereal and faint sweetish odor. Non-flammablematerial. Overexposure may cause dizziness and loss of concentration. At higher levels, CNS depression andcardiac arrhythmia may result from exposure. Vapors displace air and can cause asphyxiation in confinedspaces. At higher temperatures, ( 250 C), decomposition products may include Hydrofluoric Acid (HF) andcarbonyl halides.POTENTIAL HEALTH HAZARDSSKIN: Irritation would result from a defatting action on tissue. Liquid contact could cause frostbite.EYES: Liquid contact can cause severe irritation and frostbite. Mist may irritate.INHALATION: R-410A is low in acute toxicity in animals. When oxygen levels in air are reduced to 12-14% bydisplacement, symptoms of asphyxiation, loss of coordination, increased pulse rate and deeperrespiration will occur. At high levels, cardiac arrhythmia may occur.INGESTION: Ingestion is unlikely because of the low boiling point of the material. Should it occur, discomfort inthe gastrointestinal tract from rapid evaporation of the material and consequent evolution of gaswould result. Some effects of inhalation and skin exposure would be expected.DELAYED EFFECTS: None known.

R-410A3.COMPOSITION / INFORMATION ON INGREDIENTSINGREDIENT NAMEDifluoromethanePentafluoroethaneCAS NUMBER75-10-5354-33-6WEIGHT %5050COMMON NAME and SYNONYMSR-410A; HFC410AThere are no impurities or stabilizers that contribute to the classification of the material identified in Section 24.FIRST AID MEASURESSKIN: Promptly flush skin with water until all chemical is removed. If there is evidence of frostbite, bathe (do not rub)with lukewarm (not hot) water. If water is not available, cover with a clean, soft cloth or similar covering. Getmedical attention if symptoms persist.EYES: Immediately flush eyes with large amounts of water for at least 15 minutes (in case of frostbite water should belukewarm, not hot) lifting eyelids occasionally to facilitate irrigation. Get medical attention if symptoms persist.INHALATION: Immediately remove to fresh air. If breathing has stopped, give artificial respiration. Use oxygen asrequired, provided a qualified operator is available. Get medical attention. Do not give epinephrine(adrenaline).INGESTION:Ingestion is unlikely because of the physical properties and is not expected to be hazardous. Do not inducevomiting unless instructed to do so by a physician.ADVICE TO PHYSICIAN: Because of the possible disturbances of cardiac rhythm, catecholamine drugs, such asepinephrine, should be used with special caution and only in situations of emergency lifesupport. Treatment of overexposure should be directed at the control of symptoms and theclinical conditions.5.FIRE FIGHTING MEASURESFLAMMABLE PROPERTIESFLASH POINT:Gas, not applicable per DOT regulationsFLASH POINT METHOD:Not applicableAUTOIGNITION TEMPERATURE: 750 CUPPER FLAME LIMIT (volume % in air):None by ASTM D-56-82LOWER FLAME LIMIT (volume % in air):None by ASTM E-681FLAME PROPAGATION RATE (solids):Not applicableOSHA FLAMMABILITY CLASS:Not applicableEXTINGUISHING MEDIA:Use any standard agent – choose the one most appropriate for type of surrounding fire (material itself is notflammable)SDS:R-410APage 2 of 8Current Issue Date: January 04, 2021

R-410AUNUSUAL FIRE AND EXPLOSION HAZARDS:R-410A is not flammable at ambient temperatures and atmospheric pressure. However, this material will becomecombustible when mixed with air under pressure and exposed to strong ignition sources.Contact with certain reactive metals may result in formation of explosive or exothermic reactions under specificconditions (e.g. very high temperatures and/or appropriate pressures).SPECIAL FIRE FIGHTING PRECAUTIONS/INSTRUCTIONS:Firefighters should wear self-contained, NIOSH-approved breathing apparatus for protection against possible toxicdecomposition products. Proper eye and skin protection should be provided. Use water spray to keep fire-exposedcontainers cool.6.ACCIDENTAL RELEASE MEASURESIN CASE OF SPILL OR OTHER RELEASE:(Always wear recommended personal protective equipment.)Evacuate unprotected personnel. Product dissipates upon release. Protected personnel should remove ignitionsources and shut off leak, if without risk, and provide ventilation. Unprotected personnel should not return to theaffected area until air has been tested and determined safe, including low-lying areas.Spills and releases may have to be reported to Federal and/or local authorities. See Section 15 regarding reportingrequirements.7.HANDLING AND STORAGENORMAL HANDLING:(Always wear recommended personal protective equipment.)Avoid breathing vapors and liquid contact with eyes, skin or clothing. Do not puncture or drop cylinders, exposethem to open flame or excessive heat. Use authorized cylinders only. Follow standard safety precautions forhandling and use of compressed gas cylinders.R-410A should not be mixed with air above atmospheric pressure for leak testing or any other purpose.STORAGE RECOMMENDATIONS:Store in a cool, well-ventilated area of low fire risk and out of direct sunlight. Protect cylinder and its fittings fromphysical damage. Storage in subsurface locations should be avoided. Close valve tightly after use and when empty.INCOMPATIBILITIES:Freshly abraded aluminum surfaces at specific temperatures and pressures may cause a strong exothermic reaction.Chemically reactive metals: potassium, calcium, powdered aluminum, magnesium, and zinc.8.EXPOSURE CONTROLS / PERSONAL PROTECTIONENGINEERING CONTROLS:Provide local ventilation at filling zones and areas where leakage is probable. Mechanical (general) ventilation maybe adequate for other operating and storage areas.PERSONAL PROTECTIVE EQUIPMENTSKIN PROTECTION:Skin contact with refrigerant may cause frostbite. General work clothing and gloves (leather) should provideadequate protection. If prolonged contact with the liquid or gas is anticipated, insulated gloves constructed of PVA,SDS:R-410APage 3 of 8Current Issue Date: January 04, 2021

R-410Aneoprene or butyl rubber should be used. Any contaminated clothing should be promptly removed and washedbefore reuse.EYE PROTECTION:For normal conditions, wear safety glasses. Where there is reasonable probability of liquid contact, wear chemicalsafety goggles.RESPIRATORY PROTECTION:None generally required for adequately ventilated work situations. For accidental release or non-ventilatedsituations, or release into confined space, where the concentration may be above the PEL of 1,000 ppm, use a selfcontained, NIOSH-approved breathing apparatus or supplied air respirator. For escape: use the former or a NIOSHapproved gas mask with organic vapor canister.ADDITIONAL RECOMMENDATIONS:Where contact with liquid is likely, such as in a spill or leak, impervious boots and clothing should be worn. Highdose-level warning signs are recommended for areas of principle exposure. Provide eyewash stations and quickdrench shower facilities at convenient locations. For tank cleaning operations, see OSHA regulations, 29 CFR1910.132 and 29 CFR 1910.133.EXPOSURE GUIDELINESINGREDIENT NAMEDifluoromethanePentafluoroethane*ACGIH TLVNoneNoneOSHA PELNoneNoneOTHER LIMIT*1000 ppm TWA (8hr)*1000 ppm TWA (8hr) Workplace Environmental Exposure Level (AIHA)OTHER EXPOSURE LIMITS FOR POTENTIAL DECOMPOSITION PRODUCTS:Hydrogen Fluoride: ACGIH TLV: 2 ppm ceiling, 0.5ppm TLV-TWA9.PHYSICAL AND CHEMICAL PROPERTIESAPPEARANCE:PHYSICAL STATE:MOLECULAR WEIGHT:CHEMICAL FORMULA:ODOR:SPECIFIC GRAVITY (water 1.0):SOLUBILITY IN WATER (weight %):pH:BOILING POINT:FREEZING POINT:VAPOR PRESSURE:Clear, colorless liquid and vaporGas at ambient temperatures72.6CH2F2, CHF2CF3Faint ethereal odor1.08 @ 21.1 C (70 F)UnknownNeutral-48.5 C (-55.4 F)Not determined215.3 psia @ 70 F490.2 psia @ 130 FVAPOR DENSITY (air 1.0):3.0EVAPORATION RATE: 1COMPARED TO: CC14 1% VOLATILES:100ODOR THRESHHOLD:Not establishedFLAMMABILITY:Not applicableLEL/UEL:None/NoneRELATIVE DENSITY:1.08 g/cm3 at 21.1 CPARTITION COEFF (n-octanol/water) Not applicableSDS:R-410APage 4 of 8Current Issue Date: January 04, 2021

R-410AAUTO IGNITION TEMP: 750 CDECOMPOSITION TEMPERATURE: 250 CVISCOSITY:Not applicableFLASH POINT:Not applicable(Flash point method and additional flammability data are found in Section 5.)10. STABILITY AND REACTIVITYNORMALLY STABLE? (CONDITIONS TO AVOID):The product is stable.Do not mix with oxygen or air above atmospheric pressure. Any source of high temperature, such as lightedcigarettes, flames, hot spots or welding may yield toxic and/or corrosive decomposition products.INCOMPATIBILITIES:(Under specific conditions: e.g. very high temperatures and/or appropriate pressures) – Freshly abraded aluminumsurfaces (may cause strong exothermic reaction). Chemically active metals: potassium, calcium, powderedaluminum, magnesium and zinc.HAZARDOUS DECOMPOSITION PRODUCTS:Halogens, halogen acids and possibly carbonyl halides.HAZARDOUS POLYMERIZATION:Will not occur.11. TOXICOLOGICAL INFORMATIONIMMEDIATE (ACUTE) EFFECTS:Difluoromethane:LC50 : Inhalation 4 hr. (rat) - 520,000 ppmPentafluoroethane:Cardiac Sensitization threshold (dog) 100,000 ppmDELAYED (SUBCHRONIC AND CHRONIC) EFFECTS:Teratology – negativeSubchronic inhalation (rat) NOEL – 50,000 ppmREPEATED DOSE TOXICITY:Lifetime inhalation exposure of male rats was associated with a small increase in salivary gland fibrosarcomas.OTHER DATA:Not active in four genetic studiesFURTHER INFORMATION:Acute effects of rapid evaporation of the liquid may cause frostbite. Vapors are heavier than air and can displaceoxygen causing difficulty breathing or suffocation. May cause cardiac arrhythmia.POTENTIAL HEALTH HAZARDSSKIN: Irritation would result from a defatting action on tissue. Liquid contact could cause frostbite.EYES: Liquid contact can cause severe irritation and frostbite. Mist may irritate.SDS:R-410APage 5 of 8Current Issue Date: January 04, 2021

R-410AINHALATION: R-410A is low in acute toxicity in animals. When oxygen levels in air are reduced to 12-14% bydisplacement, symptoms of asphyxiation, loss of coordination, increased pulse rate and deeperrespiration will occur. At high levels, cardiac arrhythmia may occur.INGESTION: Ingestion is unlikely because of the low boiling point of the material. Should it occur, discomfort inthe gastrointestinal tract from rapid evaporation of the material and consequent evolution of gaswould result. Some effects of inhalation and skin exposure would be expected.DELAYED EFFECTS: None known.Ingredients found on one of the OSHA designated carcinogen lists are listed below.INGREDIENT NAMENo ingredients listed in this sectionNTP STATUSIARC STATUSOSHA LIST12. ECOLOGICAL INFORMATIONDegradability (BOD):R-410A is a gas at room temperature; therefore, it is unlikely to remain in water.Octanol Water Partition Coefficient: Log Pow 1.48 (pentafluoroethane), 0.21 (difluoromethane)13. DISPOSAL CONSIDERATIONSRCRAIs the unused product a RCRA hazardous waste if discarded?If yes, the RCRA ID number is:Not a hazardous waste.Not applicable.OTHER DISPOSAL CONSIDERATIONS:Disposal must comply with federal, state, and local disposal or discharge laws. R-410A is subject to U.S.Environmental Protection Agency Clean Air Act Regulations Section 608 in 40 CFR Part 82 regarding refrigerant recycling.The information offered here is for the product as shipped. Use and/or alterations to the product such as mixing with othermaterials may significantly change the characteristics of the material and alter the RCRA classification and the properdisposal method.14. TRANSPORT INFORMATIONUS DOT ID NUMBER:US DOT PROPER SHIPPING NAME:US DOT HAZARD CLASS:US DOT PACKING GROUP:UN3163Liquefied gas, n.o.s., (Pentafluoroethane, Difluoromethane)2.2Not applicableFor additional information on shipping regulations affecting this material, contact the information number found in Section 1.15. REGULATORY INFORMATIONTOXIC SUBSTANCES CONTROL ACT (TSCA)TSCA INVENTORY STATUS: Components listed on the TSCA inventorySDS:R-410APage 6 of 8Current Issue Date: January 04, 2021

R-410AOTHER TSCA ISSUES:Subject to Section 12(b) export notification. May contain 0-10ppm Ethane, 2chloro-1,1,1-trifluoro, CAS#75-88-7SARA TITLE III / CERCLA“Reportable Quantities” (RQs) and/or “Threshold Planning Quantities” (TPQs) exist for the following ingredients.INGREDIENT NAMESARA / CERCLA RQ (lb.)SARA EHS TPQ (lb.)No ingredients listed in this sectionSpills or releases resulting in the loss of any ingredient at or above its RQ requires immediate notification tothe National Response Center [(800) 424-8802] and to your Local Emergency Planning Committee.SECTION 311 HAZARD CLASS:IMMEDIATE PRESSURESARA 313 TOXIC CHEMICALS:The following ingredients are SARA 313 “Toxic Chemicals”. CAS numbers and weight percents are found inSection 2.INGREDIENT NAMENo ingredients listed in this sectionCOMMENTSTATE RIGHT-TO-KNOWIn addition to the ingredients found in Section 2, the following are listed for state right-to-know purposes.INGREDIENT NAMENo ingredients listed in this sectionWEIGHT %COMMENTADDITIONAL REGULATORY INFORMATION:R-410A is subject to U.S. Environmental Protection Agency Clean Air Act Regulations at 40 CFR Part 82.WARNING: Do not vent to the atmosphere. To comply with provisions of the U.S. Clean Air Act, any residualmust be recovered. Contains Pentafluoroethane (HFC-125) and Difluoromethane (HFC-32), greenhouse gaseswhich may contribute to global warming.WHMIS CLASSIFICATION (CANADA):This product has been evaluated in accordance with the hazard criteria of the CPR and the MSDS contains all theinformation required by the CPR.FOREIGN INVENTORY STATUS:EU – EINECS # 2065578 – HFC-12516. OTHER INFORMATIONCURRENT ISSUE DATE:PREVIOUS ISSUE DATE:January 04, 2021April, 2018OTHER INFORMATION:HMIS Classification: Health – 1, Flammability – 1, Reactivity – 0NFPA Classification: Health – 2, Flammability – 1, Reactivity – 0ANSI / ASHRAE 34 Safety Group – A1Regulatory Standards:1. OSHA regulations for compressed gases: 29 CFR 1910.101SDS:R-410APage 7 of 8Current Issue Date: January 04, 2021

R-410A2.DOT classification per 49 CFR 172.101Toxicity information per PAFT TestingDISCLAIMER:National Refrigerants, Inc. believes that the information and recommendations contained herein (including data andstatements) are accurate as of the date hereof. NO WARRANTY OF FITNESS FOR ANY PARTICULAR PURPOSE,WARRANTY OF MERCHANTABILITY, OR ANY OTHER WARRANTY, EXPRESSED OR IMPLIED, IS MADECONCERNING THE INFORMATION PROVIDED HEREIN. The information provided herein relates only to the specificproduct designated and may not be valid where such product is used in combination with any other methods or use of theproduct and of the information referred to herein are beyond the control of National Refrigerants. National Refrigerantsexpressly disclaims any and all liability as to any results obtained or arising from any use of the product or reliance on suchinformation.SDS:R-410APage 8 of 8Current Issue Date: January 04, 2021

R-410A Safety Data Sheet R-410A 1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME: R-410A OTHER NAME: Difluoromethane, Pentafluoroethane USE: Refrigerant Gas DISTRIBUTOR: National Refrigerants, Inc. 661 Kenyon Avenue Bridgeton, New Jersey 08302